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Build and interpret polygenic risk scores for complex diseases using genome-wide association study (GWAS) data.

Risk Metrics Calculation \n Comprehensive risk measurement toolkit for portfolio management, including Value at Risk, Expected Shortfall, and drawdown analysis. \n Use this skill when \n \n Measuring portfolio risk \n Implementing risk limits \n Building risk dashboards \n Calculating risk-adjusted returns \n Setting position sizes \n Regulatory reporting \n \n Do not use this skill when \n \n The task is unrelated to risk metrics calculation \n You need a different domain or tool outside this s

../../../ra-qm-team/risk-management-specialist/SKILL.md

Role: Risk Management Architect

Expert-level medical device risk management implementing ISO 14971 throughout the complete product lifecycle with comprehensive risk analysis, evaluation, control, and post-production monitoring capabilities.

Risk assessment is a systematic process of identifying potential threats to project success and developing strategies to mitigate, avoid, or accept them.

Identifies high-risk dependencies vulnerable to exploitation or takeover through systematic supply chain analysis. \n \n Evaluates all project dependencies against six risk criteria: single maintainers, unmaintained status, low popularity, high-risk features (FFI, deserialization), past CVEs, and missing security contacts \n Uses the gh CLI tool to query accurate GitHub metrics (stars, open issues, maintainer info) for each dependency \n Generates a structured markdown report with flagged high-r

Structured legal risk assessment using severity-by-likelihood matrix with escalation guidance. \n \n Evaluates risks across two dimensions (severity 1–5 and likelihood 1–5) to calculate a risk score determining classification as low (green), medium (yellow), high (orange), or critical (red) \n Provides escalation criteria and recommended actions for each risk level, from acceptance and monitoring for low-risk items to immediate senior counsel and outside counsel engagement for critical risks \n

You are a risk manager specializing in portfolio protection and risk measurement.

Credit risk data cleaning and variable screening pipeline for pre-loan modeling. \n \n Executes 11 independent steps covering data loading, abnormal period filtering, missing rate analysis, low-IV and high-PSI variable removal, null importance denoising, and correlation-based feature elimination \n Supports organization-level analysis with separate modeling and out-of-sample (OOS) sample handling, plus multi-process acceleration for IV and PSI calculations \n Generates comprehensive Excel report