Nearest gene is often wrong. Use L2G (locus-to-gene) scores from Open Targets which integrate eQTL, chromatin interaction, and distance data. L2G > 0.5 is a strong prediction; positional mapping alone should not be used to claim a causal gene. A single GWAS study with p < 5e-8 is suggestive — replication across independent cohorts is required for high confidence. GWAS hits are associations in the studied population; effect sizes and even the implicated gene can differ across ancestries due
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Before installing skills in Cursor, ensure your development environment meets these requirements:
node --versiontooluniverse-gwas-trait-to-geneExecute the skills CLI command in your project's root directory to begin installation:
Package manager
npx skills add https://github.com/mims-harvard/tooluniverse --skill tooluniverse-gwas-trait-to-geneFetches tooluniverse-gwas-trait-to-gene from mims-harvard/tooluniverse and configures it for Cursor.
The CLI shows a list of agents. Use arrow keys and space to select Cursor:
Confirm successful installation by checking the skill directory location:
Restart Cursor to activate tooluniverse-gwas-trait-to-gene. Access via /tooluniverse-gwas-trait-to-genein your agent's command palette.
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npx skills add https://github.com/mims-harvard/tooluniverse --skill tooluniverse-gwas-trait-to-geneWorks with
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15-45 minutes depending on use case complexity
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Use when skill capabilities match your task, clear ROI on time saved, and you can validate outputs. Best for repetitive tasks, learning, and quality improvement.
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Registry listing for tooluniverse-gwas-trait-to-gene matched our evaluation — installs cleanly and behaves as described in the markdown.
tooluniverse-gwas-trait-to-gene reduced setup friction for our internal harness; good balance of opinion and flexibility.
tooluniverse-gwas-trait-to-gene has been reliable in day-to-day use. Documentation quality is above average for community skills.
tooluniverse-gwas-trait-to-gene reduced setup friction for our internal harness; good balance of opinion and flexibility.
Useful defaults in tooluniverse-gwas-trait-to-gene — fewer surprises than typical one-off scripts, and it plays nicely with `npx skills` flows.
I recommend tooluniverse-gwas-trait-to-gene for anyone iterating fast on agent tooling; clear intent and a small, reviewable surface area.
tooluniverse-gwas-trait-to-gene is among the better-maintained entries we tried; worth keeping pinned for repeat workflows.
Registry listing for tooluniverse-gwas-trait-to-gene matched our evaluation — installs cleanly and behaves as described in the markdown.
Useful defaults in tooluniverse-gwas-trait-to-gene — fewer surprises than typical one-off scripts, and it plays nicely with `npx skills` flows.
I recommend tooluniverse-gwas-trait-to-gene for anyone iterating fast on agent tooling; clear intent and a small, reviewable surface area.
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